Area of Study 1:  Genetics

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Outcome:
  • Analyse the relationship between nucleic acids and proteins


The relationship between nucleic acids and proteins

  • Nucleic acids as information molecules that encode instructions for the synthesis of proteins 
  • The structure of DNA, the three main forms of RNA (mRNA, rRNA and tRNA) and a comparison of their respective nucleotides
  • The genetic code as a universal triplet code that is degenerate and the steps in gene expression, including transcription, RNA processing in eukaryotic cells and translation by ribosomes
  • The structure of genes: exons, introns and promoter and operator regions
  • The basic elements of gene regulation: prokaryotic trp operon as a simplified example of a regulatory process
  • Amino acids as the monomers of a polypeptide chain and the resultant hierarchical levels of structure that give rise to a functional protein
  • Proteins as a diverse group of molecules that collectively make an organism’s proteome, including enzymes as catalysts in biochemical pathways
  • The role of rough endoplasmic reticulum, Golgi apparatus and associated vesicles in the export of proteins from a cell via the protein secretory pathway


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